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Daniel D Gretler Selected Research

voxelotor

1/2019Pharmacokinetics and pharmacodynamics of voxelotor (GBT440) in healthy adults and patients with sickle cell disease.
1/2019A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease.

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Daniel D Gretler Research Topics

Disease

4Hemorrhage
05/2013 - 12/2009
2Sickle Cell Anemia (Hemoglobin S Disease)
01/2019 - 01/2019
2Myocardial Infarction
06/2012 - 12/2009
2Acute Coronary Syndrome
03/2004 - 10/2003
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
05/2024
1Hemolytic Anemia
01/2019
1Anemia
01/2019
1Hemolysis
01/2019
1Hypoxia (Hypoxemia)
01/2019
1Autoimmune Diseases (Autoimmune Disease)
01/2017
1Neoplasms (Cancer)
01/2017
1Experimental Arthritis
01/2017
1Stroke (Strokes)
05/2013
1Ischemic Stroke
05/2013
1Atrial Fibrillation
05/2013
1Heart Block
06/2012
1Hypotension (Low Blood Pressure)
06/2012
1Dyspnea (Shortness of Breath)
06/2012
1Bradycardia
06/2012
1Liver Failure
06/2012
1Body Weight (Weight, Body)
12/2011
1Obesity
12/2011
1Thrombosis (Thrombus)
12/2009
1ST Elevation Myocardial Infarction
12/2009
1Venous Thromboembolism
01/2009

Drug/Important Bio-Agent (IBA)

3Eptifibatide (Integrilin)FDA Link
12/2011 - 10/2003
2voxelotorIBA
01/2019 - 01/2019
2Oxygen (Dioxygen)IBA
01/2019 - 01/2019
2betrixabanIBA
05/2013 - 01/2009
2Clopidogrel (Plavix)FDA Link
06/2012 - 07/2010
2elinogrelIBA
06/2012 - 12/2009
1Cardiac MyosinsIBA
05/2024
1MYK-461IBA
05/2024
1Hemoglobins (Hemoglobin)IBA
01/2019
1Sickle HemoglobinIBA
01/2019
1Syk KinaseIBA
01/2017
14- (3- (2H- 1,2,3- triazol- 2- yl)phenylamino)- 2- (2- aminocyclohexylamino)pyrimidine- 5- carboxamideIBA
01/2017
1Warfarin (Coumadin)FDA LinkGeneric
05/2013
1EnzymesIBA
06/2012
1Aspartic Acid (Aspartate)FDA Link
06/2012
1TransferasesIBA
06/2012
1Transaminases (Aminotransferases)IBA
06/2012
1Alanine (L-Alanine)FDA Link
06/2012
1Purinergic P2 Receptors (ADP Receptor)IBA
12/2009
1Purinergic P2Y Receptor AntagonistsIBA
12/2009
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
12/2009
1Factor Xa (Coagulation Factor Xa)IBA
01/2009
1AntithrombinsIBA
10/2003
1Platelet Membrane Glycoprotein IIbIBA
10/2003
1Heparin (Liquaemin)FDA LinkGeneric
10/2003
1Glycoproteins (Glycoprotein)IBA
10/2003

Therapy/Procedure

4Therapeutics
01/2019 - 10/2003
4Percutaneous Coronary Intervention
06/2012 - 10/2003